Iodine and the Heart

Dr. Michael Donaldson says, “Iodine stabilizes the heart rhythm, lowers serum cholesterol, lowers blood pressure, and is known to make the blood thinner as well, judging by longer clotting times seen by clinicians Iodine is not only good for the cardiovascular system, it is vital. Sufficient iodine is needed for a stable rhythmic heart beat. Iodine, directly or indirectly, can normalize serum cholesterol levels and normalize blood pressure. Iodine attaches to insulin receptors and improves glucose metabolism, which is good news for people with diabetes. Iodine and iodine-rich foods have long been used as a treatment for hypertension and cardiovascular disease; yet, modern randomized studies examining the effects of iodine on cardiovascular disease have not been carried out.”[i]

Adequate iodine is necessary for proper thyroid function.
The heart is a target organ for thyroid hormones. Marked changes
occur in cardiac function in patients with hypo- or hyperthyroidism.

The country of Finland is an excellent case study of cardiovascular disease and iodine, as reviewed by Dr. Cann. Endemic goiter was common in people and in domestic animals, particularly in the eastern part of Finland away from the sea. Studies in the 1950s revealed that the major dietary difference between eastern and western Finland was iodine. The risk of death from coronary heart disease was 3.5 times higher for people with a goiter in Finland.[ii]

"Thyroid hormone is an important regulator of cardiac function and cardiovascular hemodynamics. Triiodothyronine, (T(3)), the physiologically active form of thyroid hormone, binds to nuclear receptor proteins and mediates the expression of several important cardiac genes, inducing transcription of the positively regulated genes including alpha-myosin heavy chain (MHC) and the sarcoplasmic reticulum calcium ATPase. Negatively regulated genes include beta-MHC and phospholamban, which are down regulated in the presence of normal serum levels of thyroid hormone. T(3) mediated effects on the systemic vasculature include relaxation of vascular smooth muscle resulting in decreased arterial resistance and diastolic blood pressure. In hyperthyroidism, cardiac contractility and cardiac output are enhanced and systemic vascular resistance is decreased, while in hypothyroidism, the opposite is true. Patients with subclinical hypothyroidism manifest many of the same cardiovascular changes, but to a lesser degree than that which occurs in overt hypothyroidism. Cardiac disease states are sometimes associated with the low T(3) syndrome. The phenotype of the failing heart resembles that of the hypothyroid heart, both in cardiac physiology and in gene expression. Changes in serum T(3) levels in patients with chronic congestive heart failure are caused by alterations in thyroid hormone metabolism suggesting that patients may benefit from T(3) replacement in this setting."[iii] T(3) of course is iodine dependent so the relationship between iodine and heart disease gets clearer.

Iodine-containing thyroid hormones, thyroxine (T4) and
triiodothyronine (T3), are important metabolic regulators
of cardiovascular activity with the ability to exert action on
cardiac myocytes, vascular smooth muscle, and endothelial cells.
Dr. Stephen. Hoption Cann
 
 
 
The above topic is addressed in much greater
detail in Dr Sircus's book,
"Iodine: bring Back the Universal Medicine"
Please click the image above for more information about the book.
 
 
 
 
 
 

References




[i] ibid

[ii] Cann SAH. Hypothesis: dietary iodine intake in the etiology of cardiovascular disease. J Am Coll Nutr 2006;25(1):1-11.

[iii] Thyroid hormone and the cardiovascular system. Danzi S, Klein I. Minerva Endocrinol. 2004 Sep;29(3):139-50. Review.